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CKB Drug Classes
ABL Inhibitor (pan)
8
ABL1 Inhibitor
6
Adenosine Targeting
16
Akt Inhibitor (Pan)
19
AKT Inhibitor (Pan) - ATP competitive
7
Akt1 Inhibitor
6
Akt2 Inhibitor
2
ALK Inhibitor
23
Antibiotic Antineoplastic
1
Antifungal Agent
1
Antimicrotubule Agent
12
Antisense Therapy
2
Aromatase Inhibitor
3
ATM Inhibitor
10
ATR Inhibitor
12
AURK Inhibitor (Pan)
11
Aurka Inhibitors
24
Aurkb Inhibitors
20
Aurkc Inhibitors
3
AXL Inhibitor
27
BCL-XL inhibitor
11
BCL2 Family Inhibitor
6
BCL2 inhibitor
18
BCL6 Inhibitor
3
BCR-ABL Inhibitor
27
BET Inhibitor (Pan)
30
BIRC5 Inhibitor
1
BRAF Inhibitor
20
BRD2 Inhibitor
1
BRD3 Inhibitor
2
BRD4 Inhibitor
7
BTK inhibitor
24
c-MYC Inhibitor
9
CD19 Antibody
11
CD20 Antibody
11
CD3 Antibody
26
CD33 Antibody
11
CD37 Antibody
7
CD38 Antibody
7
CD39 Antibody
3
CD40 Antibody
11
CD47 Antibody
14
CD73 Antibody
6
CD74 Antibody
3
CDK Inhibitor (Pan)
4
CDK1 Inhibitor
13
CDK2 Inhibitor
19
CDK2/4 Inhibitor
0
CDK4 Inhibitor
13
CDK4/6 Inhibitor
10
CDK5 Inhibitor
8
CDK6 Inhibitor
3
CDK7 Inhibitor
14
CDK8 Inhibitor
3
CDK9 Inhibitor
17
Chemotherapy - Alkylating
14
Chemotherapy - Anthracycline
11
Chemotherapy - Antimetabolite
12
Chemotherapy - Platinum
6
Chemotherapy - Taxane
2
CHK Inhibitor (Pan)
2
CHK1 Inhibitor
15
CHK2 Inhibitor
5
CRAF Inhibitor
12
CSF1 Antibody
2
CSF1R Antibody
4
CSF1R Inhibitor
25
CTLA4 Antibody
18
CTNNB1 Inhibitor
26
CXCR Antagonist
4
CXCR4 Inhibitor
15
DDR1 Inhibitor
8
DDR2 inhibitor
7
DLL4 Antibody
6
DNA_PK Inhibitor
6
DNMT inhibitor (Pan)
5
DNMT1 inhibitor
3
DOT1L Inhibitor
3
DYRK1A Inhibitor
4
DYRK1B Inhibitor
3
EGFR Antibody
31
EGFR Immune Cell Therapy
3
EGFR Inhibitor (Pan)
47
EGFR Inhibitor 1st gen
3
EGFR Inhibitor 2nd gen
3
EGFR Inhibitor 3rd gen
20
EHMT2 Inhibitor
5
EPHB4 Inhibitor
6
ERK Inhibitor (pan)
16
ERK1 Inhibitor
2
ERK2 Inhibitor
2
EZH1 inhibitor
3
EZH2 inhibitor
18
FAK inhibitor
13
Farnesyltransferase Inhibitor
3
FASN Inhibitor
5
FGFR Inhibitor (Pan)
18
FGFR1 Inhibitor
23
FGFR2 Antibody
3
FGFR2 Inhibitor
16
FGFR3 Antibody
3
FGFR3 Inhibitor
12
FGFR4 Antibody
1
FGFR4 Inhibitor
7
FLT3 Inhibitor
55
FOLR1-targeted Therapy
12
Gamma secretase inhibitor
12
GITR Antibody
6
GLI1/2 inhibitor
6
Glutaminase Inhibitor
3
GPC3 Antibody
3
GR Antagonist
1
GSK-3alpha Inhibitor
1
GSK-3beta Inhibitor
4
GSK3 Inhibitor (Pan)
3
HDAC Inhibitor
38
HER inhibitor (Pan)
5
HER2 (ERBB2) Antibody
50
HER2 (ERBB2) Immune Cell Therapy
3
HER2 (ERBB2) Vaccine
8
HER2 Inhibitor
26
HER3 (ERBB3) Antibody
16
HER3 Inhibitor
2
HGF Antibody
4
Hormone - Anti-androgens
29
Hormone - Anti-estrogens
18
Hormone - Anti-progestins
6
Hormone Antineoplastics
5
HRAS Inhibitor
1
HSP90 Inhibitor
35
IDH Inhibitor (Pan)
3
IDH1 Inhibitor
8
IDH2 Inhibitor
2
IDO1 Inhibitor
10
IGF-1R Inhibitor
17
IGF1/2 Antibody
2
IGF1R Antibody
8
Immune Checkpoint Inhibitor
98
IRAK1/4 Inhibitor
1
IRAK4 Inhibitor
5
JAK Inhibitor (Pan)
8
JAK Inhibitor (Pan) - ATP competitive
3
JAK1 Inhibitor
9
JAK1 Inhibitor - ATP competitive
4
JAK2 Inhibitor
17
JAK2 Inhibitor - ATP competitive
14
JAK3 Inhibitor
5
JAK3 Inhibitor - ATP competitive
4
JNK Inhibitor
4
KDM1A Inhibitor
12
KDM4 Inhibitor
2
KIT Inhibitor
51
KRAS G12C inhibitor
7
KRAS Inhibitor
6
LAG3 Antibody
12
LYN Inhibitor
3
MCL1 Inhibitor
15
MDM2 Inhibitor
20
MDM4 inhibitor
8
MEK inhibitor (Pan)
22
MEK1 Inhibitor
20
MEK2 Inhibitor
18
MERTK Antibody
1
MERTK Inhibitor
9
MET Antibody
17
MET Immune Cell Therapy
1
MET Inhibitor
52
Microbiome
4
MNK1 Inhibitor
0
MNK1/2 Inhibitor
3
MNK2 Inhibitor
0
MPS1 Inhibitor
25
MSLN Antibody
5
mTOR Inhibitor
51
mTORC1 Inhibitor
8
mTORC2 Inhibitor
2
MUC16 Targeted Therapy
7
NOTCH Inhibitor (Pan)
5
NOTCH1 Antibody
2
NOTCH1 Inhibitor
0
NOTCH2 Antibody
3
NOTCH2 Inhibitor
0
NOTCH3 Antibody
2
OX40 Antibody
10
p38 MAPK Inhibitor (Pan)
4
p38-alpha Inhibitor
1
p53 Activator
10
p53 Gene Therapy
4
p53 Inhibitor
0
p53 Vaccine
5
Pak-I Inhibitor
0
PAK1 Inhibitor
11
PARP Inhibitor (Pan)
21
PARP-1 Inhibitor
4
PARP-2 Inhibitor
1
PD-L1 Inhibitor
2
PD-L1/PD-1 antibody
68
PDGFR Inhibitor (Pan)
27
PDGFR-alpha Inhibitor
9
PDGFR-beta Inhibitor
13
PDGFRA Antibody
2
PDK-1 Inhibitor
1
PDPK1 Inhibitor
10
PI3K Inhibitor (Pan)
38
PIK3CA inhibitor
16
PIK3CB inhibitor
8
PIK3CD inhibitor
24
PIK3CG inhibitor
8
PIM Inhibitor (Pan)
9
PIM1 Inhibitor
2
PIM3 Inhibitor
1
PKA Inhibitor
2
PKC alpha Inhibitor
6
PKC beta Inhibitor
6
PKC Inhibitor (Pan)
11
PLK1 Inhibitor
16
PP2A Activator
7
PP2A Inhibitor
2
PPM1D Inhibitor
3
PRMT5 Inhibitor
8
PSMA Antibody
9
RAD51 Inhibitor
4
RAF Inhibitor (Pan)
16
RAS Inhibitor (Pan)
8
RET Inhibitor
39
RON Inhibitor
10
ROR1 Antibody
3
ROS1 Inhibitor
14
S6 Kinase Inhibitor
5
SHP2 Inhibitor
12
SIRT1 Activator
3
SIRT1 Inhibitor
5
SIRT2 Inhibitor
5
SIRT3 Inhibitor
1
SMAC Mimetic
8
SMO Inhibitor
16
SMYD3 Inhibitor
3
SRC Inhibitor
29
STAT1 Inhibitor
0
STAT3 Inhibitor
21
STAT5 Inhibitor
4
STING1 Agonist
9
SYK Inhibitor
14
Tankyrase Inhibitor
10
TGFB (Pan) Antibody
3
TGFB inhibitor
3
TGFB2 Vaccine
1
TGFBR inhibitor (pan)
2
TGFBR1 inhibitor
13
TGFBR2 Antibody
2
TGFBR2 inhibitor
0
TIE2 Inhibitor
1
TIGIT Antibody
7
TIM-3 Antibody
7
TLR Antibody
8
TNFRSF9 Antibody
12
TNK2 Inhibitor
6
TOPO Inhibitor (Pan)
3
TOPO1 inhibitor
8
TOPO2 inhibitor
4
Trk Receptor Inhibitor (Pan)
24
TrkA Receptor Inhibitor
8
TYRO3 Inhibitor
8
USP1 inhibitor
3
VEGF Antibody
11
VEGFR Inhibitor (Pan)
32
VEGFR1 Inhibitor
5
VEGFR2 Antibody
4
VEGFR2 Immune Cell Therapy
1
VEGFR2 Inhibitor
35
VEGFR3 Antibody
1
VEGFR3 Inhibitor
5
WEE1 Inhibitor
4
WNT Inhibitor
10
YAP Inhibitor
2
YES Inhibitor
3