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CKB Drug Classes
ABL Inhibitor (pan)
9
ABL1 Inhibitor
7
Adenosine Targeting
23
Akt Inhibitor (Pan)
21
AKT Inhibitor (Pan) - ATP competitive
7
Akt1 Inhibitor
6
Akt2 Inhibitor
2
ALK Inhibitor
31
Antibiotic Antineoplastic
1
Antifungal Agent
1
Antimicrotubule Agent
14
Antisense Therapy
13
Aromatase Inhibitor
3
ATM Inhibitor
13
ATR Inhibitor
16
AURK Inhibitor (Pan)
12
Aurka Inhibitors
26
Aurkb Inhibitors
21
Aurkc Inhibitors
3
AXL Antibody
5
AXL Inhibitor
29
BCL-XL inhibitor
14
BCL2 Family Inhibitor
6
BCL2 inhibitor
26
BCL6 Inhibitor
3
BCR-ABL Inhibitor
29
BET Inhibitor (Pan)
32
BIRC5 Inhibitor
1
BRAF Inhibitor
24
BRD2 Inhibitor
1
BRD3 Inhibitor
2
BRD4 Inhibitor
10
BTK inhibitor
35
c-MYC Inhibitor
12
CBP/p300 inhibitor
11
CCR8 Antibody
7
CD19 Antibody
19
CD20 Antibody
20
CD22 Immune Cell Therapy
11
CD27 Antibody
3
CD276 Antibody
10
CD3 Antibody
85
CD33 Antibody
12
CD37 Antibody
8
CD38 Antibody
18
CD39 Antibody
5
CD40 Antibody
13
CD47 Antibody
29
CD73 Antibody
11
CD74 Antibody
3
CDC7 Inhibitor
3
CDK Inhibitor (Pan)
3
CDK1 Inhibitor
13
CDK2 Inhibitor
26
CDK2/4 Inhibitor
0
CDK4 Inhibitor
16
CDK4/6 Inhibitor
13
CDK5 Inhibitor
8
CDK6 Inhibitor
6
CDK7 Inhibitor
16
CDK8 Inhibitor
5
CDK9 Inhibitor
20
CEACAM5 Antibody
4
CEACAM6 Antibody
3
Chemotherapy - Alkylating
16
Chemotherapy - Anthracycline
13
Chemotherapy - Antimetabolite
14
Chemotherapy - Platinum
7
Chemotherapy - Taxane
2
CHK Inhibitor (Pan)
2
CHK1 Inhibitor
17
CHK2 Inhibitor
7
CLDN18.2 Antibody
15
CLDN6 Antibody
5
CRAF Inhibitor
12
CSF1 Antibody
2
CSF1R Antibody
4
CSF1R Inhibitor
28
CTLA4 Antibody
26
CTLA4 Inhibitor
4
CTNNB1 Inhibitor
27
CXCR Antagonist
4
CXCR4 Inhibitor
15
DDR1 Inhibitor
9
DDR2 inhibitor
7
DGKZ Inhibitor
3
DLL4 Antibody
7
DNA_PK Inhibitor
9
DNMT inhibitor (Pan)
5
DNMT1 inhibitor
4
DOT1L Inhibitor
3
DYRK1A Inhibitor
4
DYRK1B Inhibitor
3
EGFR Antibody
51
EGFR Immune Cell Therapy
3
EGFR Inhibitor (Pan)
59
EGFR Inhibitor 1st gen
3
EGFR Inhibitor 2nd gen
5
EGFR Inhibitor 3rd gen
26
EGFR Inhibitor 4th gen
12
EHMT2 Inhibitor
5
EPHB4 Inhibitor
6
ERK Inhibitor (pan)
20
ERK1 Inhibitor
2
ERK2 Inhibitor
2
EZH1 inhibitor
5
EZH2 inhibitor
19
FAK inhibitor
15
Farnesyltransferase Inhibitor
3
FASN Inhibitor
5
FGFR Inhibitor (Pan)
25
FGFR1 Inhibitor
28
FGFR2 Antibody
3
FGFR2 Inhibitor
22
FGFR3 Antibody
3
FGFR3 Inhibitor
19
FGFR4 Antibody
1
FGFR4 Inhibitor
8
FLT3 Antibody
5
FLT3 Inhibitor
64
FOLR1-targeted Therapy
19
Gamma secretase inhibitor
13
GITR Antibody
6
GLI1/2 inhibitor
6
Glutaminase Inhibitor
3
GPC3 Antibody
3
GR Antagonist
2
GSK-3alpha Inhibitor
1
GSK-3beta Inhibitor
4
GSK3 Inhibitor (Pan)
3
HDAC Inhibitor
44
HER inhibitor (Pan)
6
HER2 (ERBB2) Antibody
63
HER2 (ERBB2) Antibody-Drug Conjugate
24
HER2 (ERBB2) Immune Cell Therapy
3
HER2 (ERBB2) Vaccine
12
HER2 Inhibitor
40
HER3 (ERBB3) Antibody
23
HER3 Inhibitor
1
HGF Antibody
4
HIF2A Inhibitor
6
Hormone - Anti-androgens
44
Hormone - Anti-estrogens
25
Hormone - Anti-progestins
6
Hormone Antineoplastics
5
HRAS Inhibitor
1
HSP90 Inhibitor
35
IDH Inhibitor (Pan)
3
IDH1 Inhibitor
8
IDH2 Inhibitor
5
IDO1 Inhibitor
12
IGF-1R Inhibitor
17
IGF1/2 Antibody
2
IGF1R Antibody
8
Immune Checkpoint Inhibitor
146
IRAK1/4 Inhibitor
2
IRAK4 Inhibitor
6
JAK Inhibitor (Pan)
9
JAK Inhibitor (Pan) - ATP competitive
3
JAK1 Inhibitor
9
JAK1 Inhibitor - ATP competitive
5
JAK2 Inhibitor
16
JAK2 Inhibitor - ATP competitive
15
JAK3 Inhibitor
6
JAK3 Inhibitor - ATP competitive
4
JNK Inhibitor
5
KDM1A Inhibitor
15
KDM4 Inhibitor
4
KIT Inhibitor
56
KRAS G12C inhibitor
32
KRAS G12D Inhibitor
8
KRAS Inhibitor
13
LAG3 Antibody
18
LCK Inhibitor
6
LYN Inhibitor
3
MAP4K1 Inhibitor
7
MCL1 Inhibitor
18
MDM2 Inhibitor
22
MDM4 inhibitor
8
MEK inhibitor (Pan)
23
MEK1 Inhibitor
25
MEK2 Inhibitor
23
MEN1-KMT2A Inhibitor
7
MERTK Antibody
1
MERTK Inhibitor
13
MET Antibody
26
MET Immune Cell Therapy
1
MET Inhibitor
58
Microbiome
5
MNK1 Inhibitor
0
MNK1/2 Inhibitor
3
MNK2 Inhibitor
0
MPS1 Inhibitor
27
MSLN Antibody
10
mTOR Inhibitor
51
mTORC1 Inhibitor
9
mTORC2 Inhibitor
2
MUC16 Targeted Therapy
8
NAMPT Inhibitor
7
NKG2A Antibody
3
NOTCH Inhibitor (Pan)
5
NOTCH1 Antibody
2
NOTCH1 Inhibitor
0
NOTCH2 Antibody
3
NOTCH2 Inhibitor
0
NOTCH3 Antibody
2
OX40 Antibody
13
p38 MAPK Inhibitor (Pan)
3
p38-alpha Inhibitor
1
p53 Activator
11
p53 Gene Therapy
4
p53 Inhibitor
0
p53 Vaccine
5
PAK1 Inhibitor
11
PARP Inhibitor (Pan)
29
PARP-1 Inhibitor
6
PARP-2 Inhibitor
1
PD-L1 Inhibitor
13
PD-L1/PD-1 antibody
110
PDGFR Inhibitor (Pan)
30
PDGFR-alpha Inhibitor
9
PDGFR-beta Inhibitor
14
PDGFRA Antibody
2
PDK-1 Inhibitor
1
PDPK1 Inhibitor
10
PI3K Inhibitor (Pan)
40
PIK3CA inhibitor
21
PIK3CB inhibitor
8
PIK3CD inhibitor
27
PIK3CG inhibitor
10
PIM Inhibitor (Pan)
9
PIM1 Inhibitor
2
PIM3 Inhibitor
1
PKA Inhibitor
2
PKC alpha Inhibitor
6
PKC beta Inhibitor
6
PKC Inhibitor (Pan)
11
PLK1 Inhibitor
18
PP2A Activator
7
PP2A Inhibitor
2
PPM1D Inhibitor
3
PRMT5 Inhibitor
15
PSMA Antibody
18
RAD51 Inhibitor
4
RAF Inhibitor (Pan)
27
RAS Inhibitor (Pan)
9
RET Inhibitor
52
RON Inhibitor
11
ROR1 Antibody
5
ROS1 Inhibitor
20
S6 Kinase Inhibitor
5
SHP2 Inhibitor
19
SIRT1 Activator
3
SIRT1 Inhibitor
5
SIRT2 Inhibitor
5
SIRT3 Inhibitor
1
SMAC Mimetic
8
SMO Inhibitor
16
SMYD3 Inhibitor
3
SOS1 Inhibitor
11
SRC Inhibitor
31
STAT1 Inhibitor
0
STAT3 Inhibitor
25
STAT5 Inhibitor
4
STING1 Agonist
18
SYK Inhibitor
15
Tankyrase Inhibitor
11
TGFB (Pan) Antibody
5
TGFB inhibitor
5
TGFB2 Vaccine
1
TGFBR inhibitor (pan)
2
TGFBR1 inhibitor
16
TGFBR2 Antibody
3
TGFBR2 inhibitor
1
TIE2 Inhibitor
3
TIGIT Antibody
19
TIM-3 Antibody
8
TLR Antibody
0
TLR4 Agonist
2
TLR7 Agonist
9
TLR8 Agonist
7
TLR9 Agonist
9
TNFRSF17 Antibody
17
TNFRSF9 Antibody
26
TNK2 Inhibitor
6
TOPO Inhibitor (Pan)
3
TOPO1 inhibitor
10
TOPO2 inhibitor
5
Trk Receptor Inhibitor (Pan)
31
TrkA Receptor Inhibitor
8
TROP2 Antibody
7
TYRO3 Inhibitor
8
USP1 inhibitor
5
USP7 Inhibitor
4
VEGF Antibody
11
VEGFA Antibody
3
VEGFR Inhibitor (Pan)
36
VEGFR1 Inhibitor
6
VEGFR2 Antibody
4
VEGFR2 Immune Cell Therapy
1
VEGFR2 Inhibitor
37
VEGFR3 Antibody
1
VEGFR3 Inhibitor
6
VSIR Antibody
5
WEE1 Inhibitor
6
WNT Inhibitor
15
YAP Inhibitor
3
YES Inhibitor
3